TO DISABLE A PROFILE,

1. Go to your Magento 2 admin panel.
2. Click on eBay present on the left navigation bar.
   
3. Click on Profile Manager.
   The Profile  Manager Grid appears as shown below:
   
4. Select the profile(s) that you want to disable by checking the corresponding boxes.
5. On the top left of the page, click the Actions drop-down.
   
6. When the menu appears, select Disable
7. The selected profile(s) will get disabled and a success message appears.